Dr. ir Sander Deridder

Dr. ir. Sander Deridder

Telephone: 02.629.3318
E-mail: sderidde@vub.ac.be
Office: 5G216
Degree obtained: Doctor in engineering sciences
Function: post-doctoral researcher (funded by FWO)

 
 
 
 
 
 
 

General introduction

I study mass transfer in chromatographic packings in liquid chromatography (LC) by means of computational fluid dynamics (CFD) simulations. I teach Heat and Mass Transfer in 3rd Bachelor Electronics and Information Technology.

Research

The research I am conducting is about peak dispersion in packings of liquid chromatography columns. Peak dispersion has an important influence on the resolution of a chromatographic separation and is the result of the complex interaction between flow and diffusion. By means of computational fluid dynamics (CFD) this interaction is studied in an attempt to get new insights into how peak dispersion arises. Those insights will hopefully lead towards a minimization of the peak dispersion and a higher separation resolution.

Selected publications

  • G. Desmet, S. Deridder, Effective medium theory expressions for the effective diffusion in chromatographic beds filled with porous, non-porous and porous-shell particles and cylinders. Part I: Theory, J. Chromatogr. A 1218 (2011) 32.
  • S. Deridder, G. Desmet, Effective medium theory expressions for the effective diffusion in chromatographic beds filled with porous, non-porous and porous-shell particles and cylinders. Part II: Numerical verification and quantitative effect of solid core on expected B-term band broadening, J. Chromatogr. A 1218 (2011) 46.
  • S. Deridder, G. Desmet, Calculation of the geometrical three-point parameter constant appearing in the second order accurate effective medium theory expression for the B-term diffusion coefficient in fully porous and porous-shell random sphere packings, J. Chromatogr. A 1223 (2012) 35.
  • S. Deridder, G. Desmet, New insights in the velocity dependency of the external mass transfer coefficient in 2D and 3D porous media for liquid chromatography, J. Chromatogr. A 1227 (2012) 194.
  • S. Deridder, A. Vanmessen, K. Nakanishi, G. Desmet, D. Cabooter, Experimental and numerical validation of the effective medium theory for the B-term band broadening in 1st and 2nd generation monolithic silica columns, J. Chromatogr. A 1351 (2014) 46.

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